Zotrim Review
How Does Zotrim Claim to Work?
Zotrim’s claimed main method of action is to help control hunger/appetite by boosting satiety – the feeling of fullness - so you eat smaller portions and snack less.
This would be an incredibly powerful tool in the fight against being over-weight, as it is our hunger and appetite which is our greatest and strongest enemy, when it comes to losing weight. (I discuss the bodies powerful mechanism of increased appetite in response to dieting, in more detail on page 3).
Are there Double-Blind, Placebo Controlled Studies to Prove the Product’s Effectiveness?
When reviewing the efficacy of any weight loss product; the most important consideration is the existence of double-blind, placebo controlled studies, which provide reliable scientific evidence of the effectiveness of the product.
Zotrim is one of the few products we have found on the market at present, whose claims have been substantiated in this way.
An Overview of The Science Behind Zotrim
Zotrim has been independently investigated in five studies.
In summary, the total 223 subjects that took Zotrim over the whole series of studies, lost an average of 0.7kg per each 10-day period.
In the key study (1) 47 overweight subjects took either Zotrim or a placebo for 45 days. Those taking Zotrim lost an average of 5.1kg (11.2lbs) compared to just 0.3kg (0.7lbs) with the placebo.
That would equate to about 8lbs a month at a rate of around 2lbs a week.
In three further studies, average losses were:
2.3kg over 28 days in 48 subjects wishing to lose weight (4),
1.8kg in weight and 4.3 cm in waistline over 28 days in 56 overweight women (5)
2.3kg in weight and 3.6 cm in waistline over 42 days in 73 overweight healthcare professionals (6)
Initial evidence for an effect of Zotrim was on slowing the rate of stomach emptying.
Using ultrasound studies with subjects who drank 400ml apple juice, the stomach emptied much more slowly (average 58 minutes) after taking one dose of Zotrim compared to those taking a placebo tablet (emptying in 38 minutes).
What this would mean in the real world, is that, if you took Zotrim with a drink with your meal; you would start to feel hungry 20 minutes later, following the meal than if you did not take Zotrim.
This was supported by a study with 20 subjects, 10 of whom took Zotrim and 10 took a placebo for 20 days (7).
Perception of fullness occurred much sooner when taking Zotrim, the average time to perceived fullness was decreased from 21.5 to 12 minutes.
What this means is that subjects who had taken Zotrim, were full after 12 minutes of eating, compared to those taking a placebo, who took 21.5 minutes to feel full, resulting in, most probably; 11.5 more minutes of eating time, which could quite easily involve the intake of a substantial amount of extra calories.
Dietitian Jane Griffin says: “I recently advised a group of ladies who had tried most things but failed to lose weight. They took Zotrim and I am amazed by the results – after just a few weeks most dropped at least a dress size.”
Costs Alot Less for each Pound of Weight Lost than both Alli and Appesat.
Analysis of the published results of each product shows that Zotrim is a much more cost-effective way to lose weight and provides quicker results.
Studies show an average cost of around £4.50 per pound of weight lost, with no reported negative side effects.
Alli costs around £37 per pound of weight lost and takes 84 days to lose just 4lbs more than the placebo(2).
This is over eight times more expensive per pound lost than Zotrim .
Appesat costs up to twelve times more than Zotrim in order to lose the same amount of weight. Published results show Appesat costs around £56 per pound of weight lost and takes 84 days to lose 8lbs more than the placebo(3).
After six weeks, trialists taking Appesat lost the same amount of weight as those taking the placebo(3), whereas those taking Zotrim lost 11lbs more than the placebo group in the same time (the equivalent of five bags of sugar!)(1).
In the BBC2 TV programme Professor Regan’s Diet Clinic (17 April 2009), Zotrim was the only natural diet pill that she managed to find with double blind placebo controlled clinical evidence of weight loss.
I have provided a link to Zotrim’s official website; where you can find more information about the product or purchase and try for yourself;


